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XANTHELASMATA

XANTHELASMATA

Xanthelasmata are localized accumulations of liquid deposits, with the typical clinical impression of yellowish or orange soft plaques commonly seen on the upper and lower eyelids, especially on the inner canthus (corner of the eye).

Their size and morphology varies, but most commonly they are permanent, progressive, appear in clusters and multiply.

They prevail in women and in middle-aged patients.

Possible pathogenic triggers may be familiar or liver disorders but most commonly there is no underlying medical cause.

Causes

  • Liver diseases (cirrhosis, hyperlipidaemia)
  • Kidney diseases (nephrotic syndrome)
  • Haematological conditions (myeloma)
  • Pancreatic diseases (pancreatitis)
  • Hormonal diseases (diabetes)
  • Medication (cyclosporine, retinoids, oestrogens, alcohol)

Treatment

  • Surgical excision
  • CO2 laser
  • Trichloroacetic acid
  • Low-fat diet
  • Medication (depending on the cause)

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